On this day in 1865…

Gregor Mendel presents his research results from his work on peas to the Nature Research Society of Brünn, initiating the modern genetics research program. In this presentation, Mendel introduces the concepts of dominant and recessive hereditary “factors.” Mendel also proposes two laws of heredity to explain his results, the Law of Segregation (that organisms inherit … Continue reading On this day in 1865…

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On this day in 1975…

Science published the paper “DNA modification mechanisms and gene activity during development” by Robin Holliday and John Pugh. In this paper, Holliday and Pugh identify the place of 5-methyl-cytosine (5mC) in base pair transitions, proposing that this methylation could play an important role in the stability or instability of cell type differentiation through the switching … Continue reading On this day in 1975…