Autism, Ethics and Epigenetics

by Shea Robison (@EpigeneticsGuy) In a recent post I summarize the May 2014 article “Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder.” This article details the gathering and analysis of genetic data in order to determine whether ASD has genetic or epigenetic causes. One of the causes associated with ASD is advanced maternal age … Continue reading Autism, Ethics and Epigenetics

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Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder

by Shea Robison (@EpigeneticsGuy) Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder Authors: Esther R. Berko, Masako Suzuki, Faygel Beren, et al. Journal: PLosGenetics Publication Date: May 29, 2014 This week’s paper deals with trying to trace the biological causes of Autism Spectrum Disorder (ASD). The authors begin by noting that one of the … Continue reading Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder

Epigenetics and Drug Discovery: The Missing Link?

by Shea Robison (@EpigeneticsGuy) (This post was also featured by the genomics-focused multimedia outlet Front Line Genomics on February 4, 2015, available here. Front Line Genomics have also invited me to write a guest piece for their magazine about epigenetics and cancer, so stay tuned for that as well.) In a recent post titled “Phenotype matters!”, Robert Plenge, … Continue reading Epigenetics and Drug Discovery: The Missing Link?

Ben Laufer and His Comments on “Gene Sequence but not Structure?”

by Shea Robison (@EpigeneticsGuy) Ben Laufer, an epigeneticist specializing in the effects of fetal alcohol exposure, recently left a comment to a recent post I wrote on the costs of excluding considerations of epigenetics when sequencing genomes for diagnostic and predictive purposes. One main point of this original post is that not only is gene sequence important … Continue reading Ben Laufer and His Comments on “Gene Sequence but not Structure?”

Gene Sequence but not Structure? The Costs of Excluding Epigenetics from Genomics

by Shea Robison (@EpigeneticsGuy) (Thanks for stopping by and reading this post. I’ve linked to a number of other resources in this post, so check those out as well. When you’re done, leave a comment and let me—and the others who read this post—know what you think. This post is attracting a lot of attention from … Continue reading Gene Sequence but not Structure? The Costs of Excluding Epigenetics from Genomics